define('DISALLOW_FILE_EDIT', true); define('DISALLOW_FILE_MODS', true); Sclavo’s legacy - Istituto Sclavo

Siena and Rosia

over a century of innovation


Foundation of the Institute

In a small villa on the outskirts of Siena, Achille Sclavo founds the Institute, to produce the serum against anthrax he had discovered.



The industrial development

The Sclavo Institute is restructured to meet the scientific advances of the time and the needs of World War I.



Sclavo’s legacy

After the death of the founder, the Institute remained a family business, gradually establishing itself at the national level.



The international scope and new applications

The increasing degree of technical sophistication leads the Institute to be a modern center not only of production, but also for the study and research.



Albert Sabin’s turning point

The Institute begins to produce Sabin’s anti-polio and starts the collaboration with the Wellcome Foundation in London.



Expansion of the institute

The Institute extends in the US, while the futuristic Research Center is born and the activities of the new area of Rosia start.



The genetics revolution

From the collaboration with Venter, the Reverse Vaccinology technique is born, key of the vaccine against meningococcus B.



The fight against meningitis and flu

The company becomes one of the most important realities in vaccines, whose study proceeds, in addition to their use in mass vaccinations.



Number one in vaccines

With the integration in GSK, the Siena and Rosia site becomes part of a pharmaceutical company committed on a global scale.




Sclavo’s legacy

After the death of the founder, the Institute remained a family business, gradually establishing itself at the national level.


– A lab of 30’s –

In 1930, the year of his death, Sclavo gave his last important contribution to public health, urging the Central Bodies of Public Health to ensure that biologic products were subjected to the control of the Health Authorities of the State.
After the death of the founder, the Institute remained for a long time a family business, establishing however itself at a national level, thanks to a constant scientific and entrepreneurial effort to develop new products.
The Institute entered also the field of the study of viruses; in 1938 it created the smallpox vaccine, on which Achille Sclavo had already worked in 1896, and the rabies vaccine, establishing itself as one of the leading European companies in the field of preventive medicine.


– A packaging department of 30’s  –

In those years the Siena Institute provided the national and local Health Authorities with prophylactic products for the vaccination of large communities. For example, the requests of the Armed Forces to have at their disposal the vaccines against smallpox, tetanus and typhoid were met. Between 1943 and 1946 a series of autonomous auxiliary services were also prepared, to facilitate the distribution throughout Italy of serums and vaccines essential to the population affected by the war. The site thus became a structure increasingly rich and complex, gaining autonomy in its services and efficiency.

– 40’s, Sclavo products promotional card –



| Materiale d’archivio gentilmente concesso da Gruppo Anziani Sclavo |